Gene MMAR_2109 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameruvC
Gene length555 bp
IdentifierMMAR_2109
Location 2540220 bp
Protein summary information
Molecular mass19564.6 Da
Isoelectric point9.4
Protein length185 amino acids
Structural information
PFAMB2HN61
Orthologs
M. tuberculosis H37RvRv2594c
Cross-references
UniProtB2HN61
Gene OntologyDna recombination, Dna repair, Crossover junction endodeoxyribonuclease activity, Magnesium ion binding, Nucleic acid binding
Enzyme Classification3.1.22.4
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionnuclease that resolves Holliday junction intermediates in genetic recombination. cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'terminal phosphate and a 3'terminal hydroxyl group [catalytic activity: endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction)].
Productcrossover junction endodeoxyribonuclease RuvC
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS25402202540774+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_2109|ruvC
VRVMGVDPGLTRCGLSLIESGQGRQLTALDVDVVRTPSDAPLSSRLLAINEAVEHWLETHRPDVVAIERVFSQQNVKTVMGTAQAGGVVALAAAKRGVEVHFHTPSEVKAAVTGNGTADKAQVTAMVTRILALQTKPTPADAADALALAICHCWRAPMIAQMAKAHALAEQQRRSYTAKLKAAR
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