Gene Mb0068c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY) |
| Comments | Mb0068c, -, len: 189 aa. Equivalent to Rv0067c,len: 189 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 189 aa overlap). Possible transcriptional regulator, highly similar except in N-terminus to T44726 probable transcription regulator from Mycobacterium leprae (189 aa), FASTA scores: opt: 829,E(): 0, (68.3% identity in 189 aa overlap). And similar to others, often many members of the tetR family, e.g. T36918 probable transcription regulator from Streptomyces coelicolor (202 aa); NP_535866.1|NC_003306 transcriptional regulator TetR family from Agrobacterium tumefaciens strain C58 (Dupont) (194 aa); UIDR_ECOLI|Q59431 uid operon repressor (gus operon repressor) from Escherichia coli (196 aa), FASTA scores: opt: 200, E(): 7.2e-06, (24.7% identity in 186 aa overlap); etc. Also similar to MTCY8D5_28 from Mycobacterium tuberculosis cosmid (229 aa), FASTA score: (32.7% identity in 168 aa overlap). Contains probable helix-turn-helix motif from aa 34 to 55 (Score 1523, +4.37 SD). |
| Functional category | Regulatory proteins |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 74656 | 75225 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0068c|Mb0068c
MAPTDRRVRADAARNRARVLEVAYQTFAADGLSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVGIEISSAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYNAELAAKVTDVALDGLRANRK
Bibliography
No article yet recorded
