Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE MATURASE
CommentsMb0072, -, len: 238 aa. Equivalent to Rv0071, len: 235 aa, from Mycobacterium tuberculosis strain H37Rv,(98.7% identity in 238 aa overlap). Possible maturase,similar to many proteins of the group II intron maturase family e.g. P95451|U77945 MATURASE-RELATED PROTEIN from PSEUDOMONAS ALCALIGENES (297 aa), FASTA scores: opt: 395,E(): 1.7e-20, (43.5% identity in 147 aa overlap); N-terminus of AAD16434.1|AF101076 maturase-related protein from Pseudomonas putida (473 aa); N-terminus of NP_437373.1|NC_003078 putative reverse transcriptasematurase protein from Sinorhizobium meliloti (453 aa); etc. Also similar to MLCL581_1 from Mycobacterium leprae. Contains 5 VDP repeats at N-terminus, these are also found in two Streptococcus plasmid hypothetical proteins Q52246|X17092 and Q54942|X66468. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 9 bp insertion (*-cggtggacc) leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (238 aa versus 235 aa).
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS7951380229+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0072|Mb0072
MSSITVSVDPVDPVDPVDPVDPVDPVDAVVAAGSDGLTVARIESEIGALEFLNELRTELKSGQFRPQPVRERKIPKPGGLGKVRRLGIPTVADRVVQAALKLVLEPIFETDFEPVSYGFRPARRAHDTIAEIHLFGTQEYRWVLDADIKACFDRIDHADLMDRVRHRIKDKRVLRLVNWQRIRHRWNWTDVRRWLTDPTGRWHPISADGITLFNPAAVPIRRYRYRGNTIPTPWTQAV
      
Bibliography
No article yet recorded