Gene Mb0268c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameaac
Gene length546 bp
IdentifierMb0268c
Location 312634 bp
Protein summary information
Molecular mass20037.7 Da
Isoelectric point6.7954
Protein length181 amino acids
Cross-references
UniProtP0A5N1
UniProtKB/TrEMBLX2BEJ5, P0A5N1
General annotation
TypeCDS
FunctionUnknown
ProductAMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE AAC (AAC(2')-IC)
CommentsMb0268c, aac, len: 181 aa. Equivalent to Rv0262c,len: 181 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 181 aa overlap). aac, aminoglycoside 2'-N-acetyltransferase (aac(2')-IC) (EC 2.3.1.-) (see citation below), highly similar to NP_302635.1|NC_002677 aminoglycoside 2'-N-acetyltransferase from Mycobacterium leprae (182 aa); Q49157|AAC2_MYCFO|AAC aminoglycoside 2'-N-acetyltransferase from Mycobacterium fortuitum (195 aa), FASTA scores: opt: 884, E(): 0, (69.1% identity in 181 aa overlap); and P94968|AAC2_MYCSM|AAC aminoglycoside 2'-N-acetyltransferase from Mycobacterium smegmatis (210 aa) (see also citation below). Also similar to Q52424|AAC2_PROST AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE from Providencia stuartii (178 aa). BELONGS TO THE AAC(2')-I FAMILY OF ACETYLTRANSFERASES. Note that previously known as aac(2')-IC.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS312634313179-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0268c|aac
MHTQVHTARLVHTADLDSETRQDIRQMVTGAFAGDFTETDWEHTLGGMHALIWHHGAIIAHAAVIQRRLIYRGNALRCGYVEGVAVRADWRGQRLVSALLDAVEQVMRGAYQLGALSSSARARRLYASRGWLPWHGPTSVLAPTGPVRTPDDDGTVFVLPIDISLDTSAELMCDWRAGDVW
Bibliography
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