Gene Mb0296 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameesxH
Gene length291 bp
IdentifierMb0296
Location 352850 bp
Protein summary information
Molecular mass10390.6 Da
Isoelectric point4.3451
Protein length96 amino acids
Orthologues
M. tuberculosisRv0288
Cross-references
UniProtP0A569
UniProtKB/TrEMBLX2BEL4
General annotation
TypeCDS
FunctionUnknown
Productlow molecular weight protein antigen 7 esxh (10 kda antigen) (cfp-7) (protein tb10.4)
CommentsMb0296, esxH, len: 96 aa. Equivalent to Rv0288,len: 96 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 96 aa overlap). esxH (alternate gene name: TB10.4), low molecular weight protein antigen 7 (10 kDa antigen) (CFP-7) (Protein TB10.4) (see citations below), ala-rich protein; member of mycobacterial protein family containing ESAT-6, very similar to MTV012_33 from Mycobacterium tuberculosis (96 aa), FASTA scores: opt: 566, E(): 0, (84.4% identity in 96 aa overlap). Alternative start codon possible position 351878 (see second citation). BELONG TO THE ESAT6 FAMILY (see first,sixth and seventh citations below).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS352850353140+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0296|esxH
MSQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQAMEDLVRAYHAMSSTHEANTMAMMARDTAEAAKWGG
Bibliography
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