Gene Mb0387c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0387c
Gene length552 bp
IdentifierMb0387c
Location 457285 bp
Protein summary information
Molecular mass19911.5 Da
Isoelectric point8.7763
Protein length183 amino acids
Orthologs
M. tuberculosis H37RvRv0380c
M. tuberculosis MTBC0mtbc0_000400
Cross-references
UniProtA0A1R3XV61
InterProIPR001537
UniProtKB/TrEMBLQ7U247
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE RNA METHYLTRANSFERASE (RNA METHYLASE)
CommentsMb0387c, -, len: 183 aa. Equivalent to Rv0380c,len: 183 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 183 aa overlap). Possible RNA methyltransferase (EC 2.1.1.-), equivalent to CAC32002.1|AL583925 possible RNA methyltransferase from Mycobacterium leprae (182 aa). Also some similarity with others methyltransferases e.g. P19396|TRMH_ECOLI|78514|JV0043 TRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE (TRNA METHYLTRANSFERASE) from Escherichia coli (229 aa), FASTA scores: opt: 227, E(): 1.4e-09, (28.9% identity in 166 aa overlap). Also similar to Rv0881, Rv3579c, Rv1644 from Mycobacterium tuberculosis.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS457285457836-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0387c|Mb0387c
MLLRDGDARNVVDAYRYWTREAIIADIDTRRHPLHVAIENFGHDANIGSVVRTANAFAVHTVHIVGRRRWNRRGAMVTDRYQRLCHHDSTTGLLEFAAGAGLTVVAVDNVPGAARLEQTALPRECLLLFGQEGPGITDDARAGAAVTVSIAQFGSTRSINAGVAAGIAMHAWIRQHADLGRAW
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