Gene Mb0460 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0460
Gene length711 bp
IdentifierMb0460
Location 543161 bp
Protein summary information
Molecular mass25357.1 Da
Isoelectric point5.3413
Protein length236 amino acids
Orthologs
M. tuberculosis H37RvRv0452
M. tuberculosis MTBC0mtbc0_000474
Cross-references
UniProtA0A1R3XVI3
InterProIPR001647, IPR009057, IPR015893
UniProtKB/TrEMBLQ7U1Z0
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN
CommentsMb0460, -, len: 236 aa. Equivalent to Rv0452, len: 236 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 236 aa overlap). Possible transcriptional regulator, similar to several putative TetR-family transcriptional regulators from Streptomyces coelicolor. Also similar in N-terminus to U1740Y|U15183|MLU15183_33 from Mycobacterium leprae (67 aa), FASTA score: (76.1% identity in 67 aa overlap). Contains probable helix-turn-helix motif at aa 44-65 (Score 1727, +5.07 SD).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS543161543871+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0460|Mb0460
MRYPLAVAQLGFQRARTEENKRQRAAALVEAARSLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLLHLAAEGWARWSGTVCEQLGEPGPMSAPRVAEALANGLAADPLFCDLLANLHLHLEQEVDVDRVIEVKRTSIAAVIALVDAIESALPALGRSGAFDILLAAYSLAATLWQIANPPERLTDAYAEEPELLPPEWNLDFAAALTRLLTATLLGLLAGSPCECRSPTR
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