Gene Mb0464c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameechA2
Gene length915 bp
IdentifierMb0464c
Location 546908 bp
Protein summary information
Molecular mass33085.8 Da
Isoelectric point4.782
Protein length304 amino acids
Orthologs
M. tuberculosis H37RvRv0456c
M. tuberculosis MTBC0mtbc0_000478
Cross-references
UniProtA0A1R3XVF0
InterProIPR001753, IPR018376
UniProtKB/TrEMBLQ7U1Y6
General annotation
TypeCDS
FunctionUnknown
ProductENOYL-COA HYDRATASE ECHA2 (ENOYL HYDRASE) (UNSATURATED ACYL-COA HYDRATASE) (CROTONASE)
CommentsMb0464c, echA2, len: 304 aa. Equivalent to Rv0456c,len 304 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 304 aa overlap). Probable echA2,enoyl-CoA hydratase (EC 4.2.1.17), similar to other enoyl-coA hydratases e.g. Q13011 PEROXISOMAL ENOYL-COA HYDRATASE-LIKE PROTEIN (328 aa), FASTA scores: opt: 209,E(): 5.3e-07, (31.7% identity in 142 aa overlap). Also similar to several other proteins from Mycobacterium tuberculosis e.g. MTCY09F9.29 FASTA score: (32.9% identity in 146 aa overlap); and MTI376.01c.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS546908547822-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0464c|echA2
MPTPDFQTLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFGGGFQHWGDAMMTDGRWDPGKDFAMVTARETGPTQKFMAIWRASKPVIAQVHGWCVGGASDYALCADIVIASEDAVIGTPYSRMWGAYLTGMWLYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEARVAEIATELARIPLSQLQAQKLIVNQAYENMGLASTQLLGGILDGLMRNTPDALEFIRTAQTQGVRAAVERRDGPFGDYSQAPPELRPDPTHVITPDGSM
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