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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productpossible amidohydrolase
CommentsMb0490c, -, len: 311 aa. Equivalent to Rv0480c,len: 340 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 311 aa overlap). Conserved hypothetical protein, equivalent, but longer 60 aa in N-terminus, to CAC31966.1|AL583925 putative hydrolase from Mycobacterium leprae (271 aa). Also similar to several hypothetical proteins and hydrolases e.g. AL096822|SCGD3_8 probable hydrolase from Streptomyces coelicolor (264 aa),FASTA scores: opt: 368, E(): 6.1e-15, (34.2% identity in 272 aa overlap); and YAUB_SCHPO|Q10166 hypothetical 35.7 kd protein c26a3.11 from S. pombe (322 aa), FASTA scores: opt: 338, E():1.4e-13, (30.3% identity in 277 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 56 bp deletion results in a different NH2 part and leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (329 aa versus 340 aa).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS569983570918-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0490c|Mb0490c
MRRARRRAQAGLPGSCARRCGALVAGPRLARMRIALAQIRSGTDPAANLQLVGKYAGEAATAGAQLVVFPEATMCRLGVPLRQVAEPVDGPWANGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKIHLYDAFGFTESRTVAPGREPVVVVVDGVRVGLTVCYDIRFPALYTELARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGDARTGVGASSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDNVAAARDRIAVLRNQTDFVQIDKAQSRG
      
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