Gene Mb0549 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepnp
Gene length795 bp
IdentifierMb0549
Location 627701 bp
Protein summary information
Molecular mass27963.7 Da
Isoelectric point6.1613
Protein length264 amino acids
Orthologues
M. tuberculosisRv0535
Cross-references
UniProtA0A1R3XW63
InterProIPR000845, IPR001369, IPR010044
UniProtKB/TrEMBLQ7U1U1
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE 5'-METHYLTHIOADENOSINE PHOSPHORYLASE PNP (MTA PHOSPHORYLASE)
CommentsMb0549, pnp, len: 264 aa. Equivalent to Rv0535,len: 264 aa, from Mycobacterium tuberculosis strain H37R,(100.0% identity in 264 aa overlap). Probable pnp,5'-methylthioadenosine phosphorylase (EC 2.4.2.28), highly similar to others e.g. CAB90972.1|AL355832 putative methylthioadenosine phosphorylase from Streptomyces coelicolor (280 aa); etc. Also similar to Rv3307|deoD PROBABLE PURINE NUCLEOSIDE PHOSPHORYLASE (EC 2.4.2.1) from Mycobacterium tuberculosis (268 aa). BELONGS TO THE PNP/MTAP FAMILY 2 OF PHOSPHORYLASES. Gene name could be inappropriate.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS627701628495+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0549|pnp
MHNNGRMLGVIGGSGFYTFFGSDTRTVNSDTPYGQPSAPITIGTIGVHDVAFLPRHGAHHQYSAHAVPYRANMWALRALGVRRVFGPCAVGSLDPELEPGAVVVPDQLVDRTSGRADTYFDFGGVHAAFADPYCPTLRAAVTGLPGVVDGGTMVVIQGPRFSTRAESQWFAAAGCNLVNMTGYPEAVLARELELCYAAIALVTDVDAGVAAGDGVKAADVFAAFGENIELLKRLVRAAIDRVADERTCTHCQHHAGVPLPFELP
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