Gene Mb0601 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemce2r
Gene length723 bp
IdentifierMb0601
Location 685653 bp
Protein summary information
Molecular mass26509.2 Da
Isoelectric point5.0509
Protein length240 amino acids
Orthologues
M. tuberculosisRv0586
Cross-references
UniProtP67742
UniProtKB/TrEMBLX2BFB8, P67742
General annotation
TypeCDS
FunctionUnknown
Productprobable transcriptional regulatory protein mce2r (gntr-family)
CommentsMb0601, -, len: 240 aa. Equivalent to Rv0586, len: 240 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 240 aa overlap). Probable transcriptional regulator, GntR family, similar to many e.g. P33233|LLDR_ECOLI putative L-lactate dehydrogenase operon regulatory protein from Escherichia coli (258 aa),FASTA scores: opt: 225, E(): 9.3e-08, (26.7% identity in 232 aa overlap); etc. Also similar to other M. tuberculosis transcriptional regulators GntR proteins e.g. Rv3060c, Rv0792c, etc. Contains PS00043 Bacterial regulatory proteins, gntR family signature and probable helix-turn helix motif from aa 35-56 (Score 1531, +4.40 SD).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS685653686375+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0601|mce2r
MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAALTTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMAVLVSQASRQ
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