Gene Mb0657 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namesecE1
Gene length486 bp
IdentifierMb0657
Location 734973 bp
Protein summary information
Molecular mass16956.4 Da
Isoelectric point10.2983
Protein length161 amino acids
Cross-references
UniProtP0A5Z1
UniProtKB/TrEMBLX2BFN4, P0A5Z1
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PREPROTEIN TRANSLOCASE SECE1
CommentsMb0657, secE1, len: 161 aa. Equivalent to Rv0638,len: 161 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 161 aa overlap). Probable secE1,preprotein translocase (tail-anchored membrane protein),highly similar at C-terminal half to others e.g. P36690|SECE_STRGR PREPROTEIN TRANSLOCASE SECE SUBUNIT from Streptomyces griseus (86 aa), FASTA scores: opt: 220, E(): 4.6e-06, (35.4% identity in 96 aa overlap); P16920|SECE_ECOLI preprotein translocase sece subunit from Escherichia coli strains K12 and O157:H7 (127 aa), FASTA scores: opt: 122, E(): 0.34, (37.0% identity in 54 aa overlap); etc. Contains PS01067 Protein secE/sec61-gamma signature. BELONGS TO THE SECE/SEC61-GAMMA FAMILY. PART OF THE PROKARYOTIC PROTEIN TRANSLOCATION APPARATUS WHICH COMPRISE SECA|Rv3240c, SECD|Rv2587c, SECE, SECF|Rv2586c,SECG|Rv1440 AND SECY|Rv0732. Note that previously known as secE.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS734973735458+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0657|secE1
MSDEGDVADEAVADGAENADSRGSGGRTALVTKPVVRPQRPTGKRSRSRAAGADADVDVEEPSTAASEATGVAKDDSTTKAVSKAARAKKASKPKARSVNPIAFVYNYLKQVVAEMRKVIWPNRKQMLTYTSVVLAFLAFMVALVAGADLGLTKLVMLVFG
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