Gene Mb0665c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelipG
Gene length906 bp
IdentifierMb0665c
Location 741470 bp
Protein summary information
Molecular mass32963.0 Da
Isoelectric point9.9877
Protein length301 amino acids
Cross-references
UniProtA0A1R3XX04
UniProtKB/TrEMBLQ7U1J8
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE LIPASE/ESTERASE LIPG
CommentsMb0665c, lipG, len: 301 aa. Equivalent to Rv0646c,len: 301 aa. from Mtycobacterium tuberculosis strain H37Rv, (100.0% identity in 301 aa overlap). Probable lipG,lipase/esterase (EC 3.1.-.-), equivalent to NP_302278.1|NC_002677 probable hydrolase from Mycobacterium leprae (304 aa). Also highly similar to various hydrolases, especially lipases e.g. AA61351.1|X88895 carboxyl esterase from Acinetobacter calcoaceticus (312 aa), FASTA scores: opt: 867, E(): 0,(50.2% identity in 279 aa overlap); etc. Also similar to transferases e.g. P77026 MACROLIDE 2'-PHOSPHOTRANSFERASE II from Escherichia coli (279 aa), FASTA scores: E(): 1.3e-14, (32.5% identity in 286 aa overlap). Similar to M. tuberculosis non-heme bromoperoxidases and epoxide hydrolases.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS741470742375-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0665c|lipG
MDIRSGTAVSGDVKLYYEDMGDLDHPPVLLIMGLGAQMLLWRTDFCARLVAKGLRVIRYDNRDVGLSTKTERHRPGQPLATRLVRSWLGLPSQAAYTLEDMAADAAALLDHLDVKHAHVVGASMGGMIAQIFAARFAQRTKTLAVIFSSNNHRFLPPPAPRALLALLTGPPPDSPRDVIVDNAVRVSKIIGSPAYPIPEDQVRAEAAESYDRNFHPWGIAQQFSAILGSGSLLRYDRRIVAPTVVIHGRADKLMRPFGGRAVARAINGARLVLIDGMGHDLPRQLWDRVIGELTRNFSEAG
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