Gene Mb0695c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemmpL5
Gene length2895 bp
IdentifierMb0695c
Location 777355 bp
Protein summary information
Molecular mass104783.0 Da
Isoelectric point5.9272
Protein length964 amino acids
Orthologs
M. tuberculosis H37RvRv0676c
M. tuberculosis MTBC0mtbc0_000715
Cross-references
UniProtA0A1R3XX34
InterProIPR004707, IPR004869
UniProtKB/TrEMBLQ7U1H4
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL5
CommentsMb0695c, mmpL5, len: 964 aa. Equivalent to Rv0676c,len: 964 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 964 aa overlap). Probable mmpL5,conserved transmembrane transport protein (see first citation below), member of RND superfamily, highly similar to other Mycobacterial proteins e.g. MTV037_14, MTCY98_8,MTCY20G9_34, MTCY4D9_15, MTCY48_8, MTCY19G5_6, MTV005_19,etc. Also similar to other Mycobacterial mmpl proteins e.g. P54881|MML4_MYCLE PUTATIVE MEMBRANE PROTEIN MMPL4 from Mycobacterium leprae (959 aa), FASTA scores: opt: 3991, E(): 0, (62.8% identity in 933 aa overlap); etc. BELONGS TO THE MMPL FAMILY. TBparse score is 0.884.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS777355780249-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0695c|mmpL5
MIVQRTAAPTGSVPPDRHAARPFIPRMIRTFAVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAMIVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVKTIVERLAPPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQMERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRNDDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQRPVPQPWPSPASARTFALV
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