Gene Mb0731
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE ARYLSULFATASE ATSAa [FIRST PART] (ARYL-SULFATE SULPHOHYDROLASE) (ARYLSULPHATASE) |
| Comments | Mb0731, atsAa, len: 148 aa. Equivalent to 5' end of Rv0711, len: 787 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 148 aa overlap). Possible atsA, arylsulfatase (EC 3.1.6.1), similar to others e.g. P51691|ARS_PSEAE arylsulfatase from Pseudomonas aeruginosa (532 aa), FASTA scores: opt: 439,E(): 2.9e-21, (30.8% identity in 552 aa overlap); etc. Also similar to other hypothetical arylsulfatases from Mycobacterium tuberculosis e.g. Rv3299c, Rv0663, etc. Contains PS00523 Sulfatases signature 1, and PS00149 Sulfatases signature 2. BELONGS TO THE SULFATASE FAMILY. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, atsA exists as a single gene. In Mycobacterium bovis, a single base transversion (g-t),introducing a stop codon, splits atsA into 2 parts, atsAa and atsAb. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 808157 | 808603 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0731|atsAa
MAPEATEAFNGTIELDIRDSEPDWGPYAAPVAPEHSPNILYLVWDDVGIATWDCFGGLVEMPAMTRVAERGVRLSQFHTTALCSPTRASLLTGRNATTVGMATIEEFTDGFPNCNGRIPADTALLPEVLAEHGYNTYCVGKWHLTPLE
Bibliography
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