Gene Mb0748c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefucA
Gene length657 bp
IdentifierMb0748c
Location 821665 bp
Protein summary information
Molecular mass23110.3 Da
Isoelectric point5.5439
Protein length218 amino acids
Orthologs
M. tuberculosis H37RvRv0727c
M. tuberculosis MTBC0mtbc0_000769
Cross-references
UniProtA0A1R3XWB0
InterProIPR001303
UniProtKB/TrEMBLQ7U1E5
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE L-FUCULOSE PHOSPHATE ALDOLASE FUCA (L-FUCULOSE-1-PHOSPHATE ALDOLASE)
CommentsMb0748c, fucA, len: 218 aa. Equivalent to Rv0727c,len: 218 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 218 aa overlap). Possible fucA,L-fuculose-1-phosphate aldolase (EC 4.1.2.17), similar to many e.g. NP_386339.1|NC_003047 PUTATIVE L-FUCULOSE PHOSPHATE ALDOLASE PROTEIN from Sinorhizobium meliloti (222 aa); P11550|FUCA_ECOLI L-FUCULOSE PHOSPHATE ALDOLASE from Escherichia strain K12 (215 aa), FASTA scores: opt: 372, E(): 4.1e-19, (34.6% identity in 185 aa overlap); etc. BELONGS TO THE ALDOLASE CLASS II FAMILY, ARAD/FUCA SUBFAMILY. COFACTOR: BINDS ONE ZINC ION PER MOLECULE.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS821665822321-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0748c|fucA
MNFVDDPESAVLAAAKDMLRRGLVEGTAGNISARRSDGNVVITPSSVDYAEMLLHDLVLVDAGGAVLHAKDGRSPSTELNLHLACYRAFDDIGSVIHSHPVWATMFAVAHEPIPACIDEFAIYCGGDVRCTEYAASGTPEVGRNAVRALEGRAAALIANHGLVAVGPRPDQVLRVTALVERTAQIVWGARALGGPVPIPEDVCRNFTGVYGYLRANPL
Bibliography
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