Gene Mb0793
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE DEHYDROGENASE/REDUCTASE |
| Comments | Mb0793, -, len: 295 aa. Equivalent to Rv0770, len: 295 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 295 aa overlap). Probable dehydrogenase/reductase, 3-hydroxyisobutyrate dehydrogenase family (EC 1.1.1.-), possibly 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) or 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60), similar to others e.g. P23523|GARR_ECOLI 2-HYDROXY-3-OXOPROPIONATE REDUCTASE (TARTRONATE SEMIALDEHYDE REDUCTASE) (TSAR) from Escherichia coli strain K12 (294 aa), FASTA scores: opt: 469, E(): 6.7e-22, (34.4% identity in 282 aa overlap); P28811|MMSB_PSEAE 3-hydroxyisobutyrate dehydrogenase (HIBADH) from Pseudomonas aeruginosa (298 aa), FASTA scores: opt: 439, E(): 4.3e-20, (34.9% identity in 269 aa overlap); etc. Also similar to others from Mycobacterium tuberculosis e.g. Rv1122 and Rv1844c. SEEMS TO BELONG TO THE 3-HYDROXYISOBUTYRATE DEHYDROGENASE FAMILY. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 865445 | 866332 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0793|Mb0793
MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPGSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET
Bibliography
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