Gene Mb0871
in Mycobacterium bovis AF2122/97
General annotation
Type | CDS |
Function | Unknown |
Product | POSSIBLE CYSTEINE SYNTHASE A CYSK2 (O-ACETYLSERINE SULFHYDRYLASE) (O-ACETYLSERINE (THIOL)-LYASE) (CSASE) |
Comments | Mb0871, cysK2, len: 372 aa. Equivalent to Rv0848,len: 372 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 372 aa overlap). Possible cysK2,cysteine synthase A (EC 4.2.99.8), but could be also a cysteine synthase B (EC 4.2.99.8) cysM2-product, similar to many e.g. NP_109408.1|NC_002682 cysteine synthase from Mesorhizobium loti (357 aa); Q44004|CYSM_ALCEU CYSTEINE SYNTHASE from Alcaligenes eutrophus strain CH34 (Ralstonia eutropha) (339 aa), FASTA scores: opt: 511, E(): 1.7e-25,(35.0% identity in 314 aa overlap); etc. BELONGS TO THE CYSTEINE SYNTHASE/CYSTATHIONINE BETA-SYNTHASE FAMILY. COFACTOR: PYRIDOXAL PHOSPHATE. Note that previously known as cysM3. |
Functional category | |
Mutant | Check for mutants available at TARGET website |
Coordinates
Type | Start | End | Orientation |
---|---|---|---|
CDS | 945693 | 946811 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0871|cysK2 MRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIVESTSGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMGTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVVS
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