Gene Mb1062c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametrcR
Gene length774 bp
IdentifierMb1062c
Location 1158410 bp
Protein summary information
Molecular mass29209.4 Da
Isoelectric point6.0621
Protein length257 amino acids
Orthologs
M. tuberculosis H37RvRv1033c
M. tuberculosis MTBC0mtbc0_001112
Cross-references
UniProtA0A1R3XX60
InterProIPR001789, IPR001867, IPR011006, IPR011991, IPR016032
UniProtKB/TrEMBLQ7U0T9
General annotation
TypeCDS
FunctionUnknown
ProductTWO COMPONENT TRANSCRIPTIONAL REGULATOR TRCR
CommentsMb1062c, trcR, len: 257 aa. Equivalent to Rv1033c,len: 257 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 257 aa overlap). trcR, two-component regulatory protein (see citations below), similar to Q50825 TWO COMPONENT RESPONSE REGULATOR from Mycobacterium tuberculosis (234 aa), FASTA scores: opt: 628, E(): 0,(46.0% identity in 226 aa overlap). Note that in vitro autophosphorylation of TrcS requires the presence of Mn2+or Ca2+as a divalent cation cofactor and subsequent transphosphorylation of TrcR is evident in the presence of TrcS-phosphate and Ca2+.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS11584101159183-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1062c|trcR
MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE
Bibliography
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