Gene Mb1120 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecelA2b
Gene length456 bp
IdentifierMb1120
Location 1216980 bp
Protein summary information
Molecular mass16404.2 Da
Isoelectric point3.7608
Protein length151 amino acids
Orthologs
M. tuberculosis H37RvRv1090
M. tuberculosis MTBC0mtbc0_001173
Cross-references
UniProtA0A1R3XXB8
InterProIPR002594, IPR008985, IPR013319
UniProtKB/TrEMBLQ7U0P2
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CELLULASE CELA2B (ENDO-1,4-BETA-GLUCANASE) (ENDOGLUCANASE) (CARBOXYMETHYL CELLULASE)
CommentsMb1120, celA2b, len: 151 aa. Equivalent to Rv1090,len: 151 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 151 aa overlap). Probable celA2b, second part of cellulase (endoglucanase) (EC 3.2.1.4), similar to C-terminus of others e.g. O08468 cellulase CEL2 from Streptomyces halstedi (377 aa), FASTA scores: opt: 554,E(): 1.2e-30, (52.0% identity in 152 aa overlap); etc. Gene appears to have been inactivated by frameshift mutations but no errors could be found that would account for this.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12169801217435+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1120|celA2b
MGTNLPTEVGQILSAPTSIDYNYPTTGVWDASYDICLDSTPKTTGVNQQEIMIWFNHQGSIQPVGSPVGNTTIEGKNFVVWDGSNGMNNAMAYVATEPIEVWSFDVMSFVDHTATMEPITDSWYLTSIRAGLEPWSDGVGLGVDSFSAKVN
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