Gene Mb1124 in Mycobacterium bovis AF2122/97
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedesA2
Gene length828 bp
IdentifierMb1124
Location 1223331 bp
Protein summary information
Molecular mass31359.5 Da
Isoelectric point4.5798
Protein length275 amino acids
Cross-references
UniProtA0A1R3XXD5
InterProIPR005067, IPR009078, IPR012348
UniProtKB/TrEMBLQ7U0P0
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA2 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE)
CommentsMb1124, desA2, len: 275 aa. Equivalent to Rv1094,len: 275 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 275 aa overlap). Possible desA2,acyl-[acyl-carrier protein] desaturase (stearoyl-ACP desaturase) (EC 1.14.19.2), equivalent to AL049491|MLCB1222_15 from Mycobacterium leprae (275 aa),FASTA score: (78.1% identity in 274 aa overlap). Also weakly similar to plant stearoyl-acyl carrier protein desaturases, and very similar to U49839|MTV043.16C|Rv0824c enzyme desA1 from Mycobacterium tuberculosis (338 aa),FASTA scores: opt: 525, E(): 8.5e-30, (32.2% identity in 270 aa overlap); and to U15182|MLU15182_32 acyl-carrier protein desaturase precursor from Mycobacterium leprae (338 aa), FASTA scores: opt: 506, E(): 1.9e-28, (34.1% identity in 261 aa overlap). TBparse score is 0.894.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12233311224158+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1124|desA2
MAQKPVADALTLELEPVVEANMTRHLDTEDIWFAHDYVPFDQGENFAFLGGRDWDPSQSTLPRTITDACEILLILKDNLAGHHRELVEHFILEDWWGRWLGRWTAEEHLHAIALREYLVVTREVDPVANEDVRVQHVMKGYRAEKYTQVETLVYMAFYERCGAVFCRNLAAQIEEPILAGLIDRIARDEVRHEEFFANLVTHCLDYTRDETIAAIAARAADLDVLGADIEAYRDKLQNVADAGIFGKPQLRQLISDRITAWGLAGEPSLKQFVTG
Bibliography
No article yet recorded