Gene Mb1202c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelipx
Gene length303 bp
IdentifierMb1202c
Location 1301195 bp
Protein summary information
Molecular mass10872.2 Da
Isoelectric point5.8726
Protein length100 amino acids
Orthologs
M. tuberculosis H37RvRv1169c
M. tuberculosis MTBC0mtbc0_001258
Cross-references
UniProtA0A1R3XYI5
InterProIPR000084
UniProtKB/TrEMBLQ7U0H3
General annotation
TypeCDS
FunctionUnknown
Productpe family protein. possible lipase lipx.
CommentsMb1202c, PE11, len: 100 aa. Equivalent to Rv1169c,len: 100 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 100 aa overlap). Member of the Mycobacterium tuberculosis PE family of proteins (see second citation below), e.g. O05297|Z93777|MTCI364.07 (99 aa), FASTA scores: opt: 209, E(): 1.6e-15, (37.4% identity in 99 aa overlap). Also simlar to the N-terminus of P77909|U76006 ESTERASE/LIPASE (EC 3.1.1.3) from Mycobacterium tuberculosis (437 aa), FASTA scores: opt: 193, E(): 4.4e-14, (37.2% identity in 94 aa overlap). Contains a helix-turn-helix motif from aa 88-109 (+2.76 SD).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13011951301497-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1202c|lipx
MSFVTTRPDSIGETAANLHEIGVTMSAHDDGVTPLITNVESPAHDLVSIVTSMLFSMHGELYKAIARQAHVIHESFVQTLQTSKTSYWLTELANRAGTST
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