Gene Mb1221 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namesigI
Gene length873 bp
IdentifierMb1221
Location 1333342 bp
Protein summary information
Molecular mass31431.1 Da
Isoelectric point6.5106
Protein length290 amino acids
Orthologues
M. tuberculosisRv1189
Cross-references
UniProtA0A1R3XZQ9
InterProIPR007627, IPR011991, IPR013249, IPR013324, IPR013325, IPR014284
UniProtKB/TrEMBLQ7U0F6
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGI
CommentsMb1221, sigI, len: 290 aa. Equivalent to Rv1189,len: 290 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 290 aa overlap). Possible sigI,alternative RNA polymerase sigma factor (see citation below), similar to several e.g. O05767|U87307 extracytoplasmic function alternative sigma factor (sigE) from M. smegmatis (204 aa), FASTA scores: opt: 239, E(): 1.3e-09, (32.9% identity in 167 aa overlap).
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13333421334214+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1221|sigI
MSQHDPVSAAWRAHRAYLVDLAFRMVGDIGVAEDMVQEAFSRLLRAPVGDIDDERGWLIVVTSRLCLDHIKSASTRRERPQDIAAWHDGDASVSSVDPADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIFGLPYQQIATTIGSQASTCRQLAHRARRKINESRIAASVEPAQHRVVTRAFIEACSNGDLDTLLEVLDPGVAGEIDARKGVVVVGADRVGPTILRHWSHPATVLVAQPVCGQPAVLAFVNRALAGVLALSIEAGKITKIHVLVQPSTLDPLRAELGGG
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