Gene Mb1405 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1405
Gene length996 bp
IdentifierMb1405
Location 1540511 bp
Protein summary information
Molecular mass37162.0 Da
Isoelectric point8.784
Protein length331 amino acids
Orthologs
M. tuberculosis H37RvRv1371
Cross-references
UniProtA0A1R3XY54
InterProIPR005804
UniProtKB/TrEMBLQ7U065
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED MEMBRANE PROTEIN
CommentsMb1405, -, len: 331 aa. Equivalent to 3' end of Rv1371, len: 489 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 331 aa overlap). Probable membrane protein. Weak similarity to delta 5 fatty acid desaturases e.g. AB022097|AB022097_1 Dictyostelium discoideum (467 aa), FASTA score: opt: 173, E(): 0.00052,(22.4% identity in 438 aa overlap); and Homo sapiens. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv1371 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base insertion (*-a) splits Rv1371 into 2 parts, Mb1404 and Mb1405, with the latter being the more likely product.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15405111541506+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1405|Mb1405
MGYFAVQGVRLVEPSWMPLWAFVIAMVLLRSSLAGFGHYALHRAQRGLNRVFNNAFDLNYVALSLVTADGHTLLHHPYTQSEVDIKKNVFTMMMRLPWLYRVPVHTIHKFGHMLSGMAIRIVDVFRITRKVGVEESYGSWRAALPHFLGSAGVRLLLVSELVVFAIAGDFWPWALQFVATLWVSTFLVVASHEFEDDTQGGAVNGEDWGIDQLEHANDLTVIGNRYVDCFLSAGLSSHRVHHVLPFQRSGFANIVTEDVLREEAAKFGVEWLPAKGFITDRLPRLCRKYLLTPSRQAKERHWGFVREHCSPAALKASASYVVAGFVGIGSV
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