Gene Mb1431c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS25
Gene length1359 bp
IdentifierMb1431c
Location 1568806 bp
Protein summary information
Molecular mass37965.2 Da
Isoelectric point5.0878
Protein length452 amino acids
Cross-references
UniProtA0A1R3XZ81
InterProIPR000084
UniProtKB/TrEMBLQ7U049
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs25
CommentsMb1431c, PE_PGRS25, len: 452 aa. Similar to Rv1396c, len: 576 aa, from Mycobacterium tuberculosis strain H37Rv, (78.1% identity in 576 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins, strong similarity to many e.g. glycine rich protein MTCY130.10C|E245019 (603 aa),FASTA scores: opt: 1945, E(): 0, (57.5% identity in 619 aa overlap). Contains PS00017 ATP/GTP-binding site motif A,similar to other PGRS-type sequences. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 372 bp deletion leads to a shorter product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (452 aa versus 576 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15688061570164-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1431c|PE_PGRS25
MSFLFAQPEMLGAAATDLASIGSAISTANAAAAAATTRVLAAGADEVSAAVAALFSGHAQTYQALSTQAAAFHQQIVQTLTSTAGAYASAEAANVEQQLLGAINAPTMALLGRPLIGHGADGAPGTGQAGGAGGILYGNGGNGGSGATGQAGGAGGAAGLIGHGGAGGLGGTGASGGAGGAGGWLWGNGGAGGNGGVGVAGDPGGVGGAGGAGGAAGLWGSGGSGGTGGQGGVGGGKSGDGGTGGIGGAGGGGGWLHGDGGAGGHGGQGGTGVSSGGNGGAGGTGGDGRGLSGSGGAGGHGGQTGVGGKVGENNFGGAGGAGGTGGLIGNGGAGGTGGKGGDGFGVFGKGGAGGTGGRGGAAGLIGDAGTGGTGGKGGTAGEDGTGGNGGTGGNGGAAVLIGNGGGGGAGGNGGAGNDGTPGNGGGGGVGGTGGTLFGQPGQPGPPGQPGPA
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