Gene Mb1502c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadE15
Gene length1830 bp
IdentifierMb1502c
Location 1650419 bp
Protein summary information
Molecular mass65923.9 Da
Isoelectric point4.9018
Protein length609 amino acids
Orthologs
M. tuberculosis H37RvRv1467c
M. tuberculosis MTBC0mtbc0_001569
Cross-references
UniProtA0A1R3XYF3
InterProIPR006091, IPR009075, IPR009100, IPR013786, IPR020953, IPR025878
UniProtKB/TrEMBLQ7U008
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ACYL-COA DEHYDROGENASE FADE15
CommentsMb1502c, fadE15, len: 609 aa. Equivalent to Rv1467c, len: 609 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 609 aa overlap). Probable fadE15, acyl-CoA dehydrogenase (EC 1.3.99.-), highly similar to NP_302639.1|NC_002677 acyl-CoA dehydrogenase from Mycobacterium leprae (611 aa). Also highly similar to many e.g. T36481 probable acyl-CoA dehydrogenase (fragment) from Streptomyces coelicolor (491 aa) (has its N-terminus very shorter); NP_384640.1|NC_003047 PUTATIVE ACYL-COA DEHYDROGENASE PROTEIN from Sinorhizobium meliloti (598 aa); ACDS_MEGEL|Q06319 acyl-CoA dehydrogenase (short-chain specific) from Megasphaera elsdenii (383 aa),FASTA scores: E(): 2e-12, (25.4% identity in 410 aa overlap); etc. Also highly similar to fadE5|Rv0244c|MTV034.10c ACYL-COA DEHYDROGENASE from M. tuberculosis (611 aa); and similar to other proteins from Mycobacterium tuberculosis.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16504191652248-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1502c|fadE15
MGHYIANVRDLEFNLLEVLDIGAVLGTGRYSDLDVDTVRTILAEAARLAEGPIAESFGYADRNPPVFDPNTHSISVPDELAKTVQAIKEAGWWRLGLAEEIGGMPAPPPLAWAVNEMIYCANPSACFFNLGPVLAQSLYIEGNDEQRRWAAEGVQRGWQATMVLTEPDAGSDVGAGRTKAFEQPDGTWHIEGVKRFISGGDVGNTAENIFHLVLARPEGAGPGTKGLSLFYVPNYLFDPDTFELGARNGVYVTGLEHKMGLKSSPTCELTFGGADVPAVGYLVGGVHNGIAQMFTVIEHARMTIGVKSAGTLSTGYLNALAFAKERVQGADLTQMTDKTAPRVTIMHHPDVRRSLMTQKAYAEGLRALYLYAAAHQDDAVAQRVSGADHDMAHRVDDLLLPIVKGVGSERAYEILTESLQTLGGSGFLVDYPLEQYIRDAKIDSLYEGTTAIQALDFFFRKIVRDHGKALQFVLAQVTHTVENIDPSLKPQAELLRTALDDITAMTGALTGYLMSAAQHSSDIYKVGLGSVRYLLAVGDLLIGWRLLVLAGVAHAALADGPSQNDEAFYRGKIAVAAFFAKNMLPKLTGVRSVIENIDDDIMRVPEDAF
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