Gene Mb1510c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1510c
Gene length564 bp
IdentifierMb1510c
Location 1659387 bp
Protein summary information
Molecular mass21269.2 Da
Isoelectric point9.2334
Protein length187 amino acids
Orthologs
M. tuberculosis H37RvRv1474c
M. tuberculosis MTBC0mtbc0_001577
Cross-references
UniProtA0A1R3Y0K1
InterProIPR001647, IPR009057, IPR011075, IPR015893
UniProtKB/TrEMBLQ7U001
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
CommentsMb1510c, -, len: 187 aa. Equivalent to Rv1474c,len: 187 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 187 aa overlap). Probable transcription regulator, equivalent to AF0021|AF002133_1 transcriptional regulator from Mycobacterium avium strain GIR10 (82 aa),FASTA scores: opt: 490, E(): 6.7e-26, (92.5% identity in 80 aa overlap). Also similar to Q59431|UIDR_ECOLI UID OPERON REPRESSOR (GUS OPERON) from Escherichia coli (196 aa), FASTA scores: opt: 192, E(): 5.8e-06, (28.5% identity in 172 aa overlap). BELONGS TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS. Helix turn helix motif predicted at aa 33-54 (+3.40 SD).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16593871659950-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1510c|Mb1510c
MPKVSEDHLAARRRQILDGARRCFAEYGYDKATVRRLEQAIGMSRGAIFHHFRDKDALFFALAREDTERMAAVASREGLIGVMRDMLAAPDQFDWLATRLEIARKLRNDPDFSRGWAERSAELAAATTDRLRRQKQANRVRDDVPSDVLRCYLDLVLDGLLARLASGEDPQRLAAVLDLVENSVRRS
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