Gene Mb1548 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadD25
Gene length1752 bp
IdentifierMb1548
Location 1696315 bp
Protein summary information
Molecular mass63167.6 Da
Isoelectric point5.005
Protein length583 amino acids
Orthologs
M. tuberculosis H37RvRv1521
M. tuberculosis MTBC0mtbc0_001628
Cross-references
UniProtA0A1R3XYJ1
InterProIPR000873
UniProtKB/TrEMBLQ7TZY1
General annotation
TypeCDS
FunctionUnknown
Productprobable fatty-acid-amp ligase fadd25 (fatty-acid-amp synthetase) (fatty-acid-amp synthase)
CommentsMb1548, fadD25, len: 583 aa. Equivalent to Rv1521,len: 583 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 583 aa overlap). Probable fadD25,fatty-acid-CoA synthetase (EC 6.2.1.-), highly similar to many e.g. P71495|U75685 ACYL-CoA SYNTHASE from Mycobacterium bovis (582 aa), FASTA scores: opt: 2486,E(): 0, (63.4% identity in 584 aa overlap); NP_301232.1|NC_002677 acyl-CoA synthetase from Mycobacterium leprae (579 aa); etc. Also highly similar to others from Mycobacterium tuberculosis e.g. fadD24 (584 aa); fadD28 (580 aa); etc.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16963151698066+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1548|fadD25
MSVVESSLPGVLRERASFQPNDKALTFIDYERSWDGVEETLTWSQLYRRTLNLAAQLREHGSTGDRALILAPQILDYVVSFIASLQAGIVAVPLSIPQGGAHDERTVSVFADTAPAIVLTASSVVDNVVEYVQPQPGQNAPAVIEVDRLDLDARPSSGSRSAAHGHPDILYLQYTSGSTRTPAGVMVSNKNLFANFEQIMTSYYGVYGKVAPPGSTVVSWLPFYHDMGFVLGLILPILAGIPAVLTSPIGFLQRPARWIQMLASNTLAFTAAPNFAFDLASRKTKDEDMEGLDLGGVHGILNGSERVQPVTLKRFIDRFAPFNLDPKAIRPSYGMAEATVYVATRKAGQPPKIVQFDPQKLPDGQAERTESDGGTPLVSYGIVDTQLVRIVDPDTGIERPAGTIGEIWVHGDNVAIGYWQKPEATERTFSATIVNPSEGTPAGPWLRTGDSGFLSEGELFIMGRIKDLLIVYGRNHSPDDIEATIQTISPGRCAAIAVSEHGAEKLVAIIELKKKDESDDEAAERLGFVKREVTSAISKSHGLSVADLVLVSPGSIPITTSGKIRRAQCVELYRQDEFTRLDA
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