Gene Mb1710 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb1710
Gene length3000 bp
IdentifierMb1710
Location 1892934 bp
Protein summary information
Molecular mass107395.0 Da
Isoelectric point6.4509
Protein length999 amino acids
Orthologues
M. tuberculosisRv1683
Cross-references
UniProtA0A1R3Y153
InterProIPR000873
UniProtKB/TrEMBLQ7VEU5
General annotation
TypeCDS
FunctionUnknown
Productpossible bifunctional enzyme; long-chain acyl-coa synthase and lipase.
CommentsMb1710, -, len: 999 aa. Equivalent to Rv1683, len: 999 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 999 aa overlap). Possible long-chain acyl-CoA synthase. Equivalent to Z95117|MLCB1351_21 possible long-chain acyl-CoA synthase from Mycobacterium leprae (1002 aa) (85.6% identity in 1002 aa overlap). Weakly similar to FATP_MOUSE|Q60714 long-chain fatty acid transport protein (646 aa), fasta scores: opt: 331, E(): 5e-08, (24.8% identity in 630 aa overlap). Also similar to O35488|AF033031 Mouse VERY-LONG-CHAIN ACYL-COA SYNTHETASE (620 aa), fasta scores: opt: 435, E(): 2.2e-12, (24.8% identity in 545 aa overlap). Weakly similar to M. tuberculosis protein MTCI364.18 (27.4% identity in 583 aa overlap) . Contains PS00120 Lipases, serine active site.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18929341895933+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1710|Mb1710
MVDLNFSMVTRPIERLVATAQNGLEVLRLGGLETGSVPSPSQIVESVPMYKLRRYFPPDNRPGQPPVGPPVLMVHPMMMSADMWDVTREDGAVGILHASGLDPWVIDFGSPDEVEGGMRRNLADHIVALSEAVDTVKDATGHDVHFVGYSQGGMFCYQAAAYRRSKDIASVVAFGSPVDTLAALPMGIPANMGAAVADFMADHVFNRLDIPSWMARMGFQMMDPLKTAKARVDFVRQLHDREALLPREQQRRFLESEGWIAWSGPAISELLKQFIAHNRMMTGGFAISGQMVTLTDITCPILAFVGEVDDIGQPASVRGIRRAAPNSEVYECLIRAGHFGLVVGSRAAQQSWPTVADWVRWISGDGTKPENIHLMADQPAEHTDSGVAFSSRVAHGIGEVSEAALALARGAADAVVAANRSVRTLAVETVRTLPRLARLGQLNDHTRISLGRIIDEQAHDAPKGEFLLFDGRVHTYEAVNRRINNVVRGLIAVGVRQGDRVGVLMETRPSALVAIAALSRLGAVAVVMRPDTDLSASVRLGRVTEILTDPTNLDAARQLPGQVLVLGGGESRDLDLPADALEQGQVIDMEKIDPDAVELPAWYRPNPGLARDLAFIAFSSADGDLVAKQITNYRWAVSAFGTASTAALGRRDTVYCLTPLHHESALLVSLGGAVVGGTRIALSRGLRPDRFVAEVRQYGVTVVSYTWAMLRDVVDDPAFVLHGNHPVRLFIGSGMPTGLWERVVEAFAPAHVVEFFATTDGQAVLANVAGAKIGSKGRPLPGAGRVELGAYDAEHDLILENDRGFVQVAGVNQVGVLLAQSRGPIDPTASVKRGVFAPADTWISTDYLFWRDDDGDYWLAGGRGSVVRTARGMVYTEPVTNALGLITGVDLAVTYGVLVRGRHVAVSAVTLLPGATITAADLTEAVASMPVGLGPDIVHVVPQLTLSGTYRPTVSALRANGIPKAGRQAWYFNSGGNEYRRLTPAVRTELTGQHRRGNA
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