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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productpossible bifunctional enzyme; long-chain acyl-coa synthase and lipase.
CommentsMb1710, -, len: 999 aa. Equivalent to Rv1683, len: 999 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 999 aa overlap). Possible long-chain acyl-CoA synthase. Equivalent to Z95117|MLCB1351_21 possible long-chain acyl-CoA synthase from Mycobacterium leprae (1002 aa) (85.6% identity in 1002 aa overlap). Weakly similar to FATP_MOUSE|Q60714 long-chain fatty acid transport protein (646 aa), fasta scores: opt: 331, E(): 5e-08, (24.8% identity in 630 aa overlap). Also similar to O35488|AF033031 Mouse VERY-LONG-CHAIN ACYL-COA SYNTHETASE (620 aa), fasta scores: opt: 435, E(): 2.2e-12, (24.8% identity in 545 aa overlap). Weakly similar to M. tuberculosis protein MTCI364.18 (27.4% identity in 583 aa overlap) . Contains PS00120 Lipases, serine active site.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18929341895933+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1710|Mb1710
MVDLNFSMVTRPIERLVATAQNGLEVLRLGGLETGSVPSPSQIVESVPMYKLRRYFPPDNRPGQPPVGPPVLMVHPMMMSADMWDVTREDGAVGILHASGLDPWVIDFGSPDEVEGGMRRNLADHIVALSEAVDTVKDATGHDVHFVGYSQGGMFCYQAAAYRRSKDIASVVAFGSPVDTLAALPMGIPANMGAAVADFMADHVFNRLDIPSWMARMGFQMMDPLKTAKARVDFVRQLHDREALLPREQQRRFLESEGWIAWSGPAISELLKQFIAHNRMMTGGFAISGQMVTLTDITCPILAFVGEVDDIGQPASVRGIRRAAPNSEVYECLIRAGHFGLVVGSRAAQQSWPTVADWVRWISGDGTKPENIHLMADQPAEHTDSGVAFSSRVAHGIGEVSEAALALARGAADAVVAANRSVRTLAVETVRTLPRLARLGQLNDHTRISLGRIIDEQAHDAPKGEFLLFDGRVHTYEAVNRRINNVVRGLIAVGVRQGDRVGVLMETRPSALVAIAALSRLGAVAVVMRPDTDLSASVRLGRVTEILTDPTNLDAARQLPGQVLVLGGGESRDLDLPADALEQGQVIDMEKIDPDAVELPAWYRPNPGLARDLAFIAFSSADGDLVAKQITNYRWAVSAFGTASTAALGRRDTVYCLTPLHHESALLVSLGGAVVGGTRIALSRGLRPDRFVAEVRQYGVTVVSYTWAMLRDVVDDPAFVLHGNHPVRLFIGSGMPTGLWERVVEAFAPAHVVEFFATTDGQAVLANVAGAKIGSKGRPLPGAGRVELGAYDAEHDLILENDRGFVQVAGVNQVGVLLAQSRGPIDPTASVKRGVFAPADTWISTDYLFWRDDDGDYWLAGGRGSVVRTARGMVYTEPVTNALGLITGVDLAVTYGVLVRGRHVAVSAVTLLPGATITAADLTEAVASMPVGLGPDIVHVVPQLTLSGTYRPTVSALRANGIPKAGRQAWYFNSGGNEYRRLTPAVRTELTGQHRRGNA
      
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