Gene Mb1779c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE FATTY-ACID-COA LIGASE FADD1 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-COA SYNTHASE) |
| Comments | Mb1779c, fadD1, len: 532 aa. Equivalent to Rv1750c,len: 532 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 532 aa overlap). Possible fadD1,fatty-acid-CoA synthetase (EC 6.2.1.-), similar in part to others e.g. O35488|VLCS_MOUSE VERY-LONG-CHAIN ACYL-COA SYNTHETASE from Mus musculus (620 aa); NP_113924.1|NM_031736 solute carrier family 27 (fatty acid transporter) member 2 from Rattus norvegicus (620 aa); NP_459076.1|NC_003197 crotonobetaine/carnitine-CoA ligase from Salmonella typhimurium (517 aa); CAIC_ECOLI|P31552 probable crotonobetaine/carnitine-coa ligase from Escherichia coli (522 aa), FASTA scores: opt: 448, E(): 1.9e-21, (25.1% identity in 502 aa overlap); etc. Also highly similar to fadD17|Rv3506|MTV023.13 PROBABLE FATTY-ACID-COA LIGASE from Mycobacterium tuberculosis (502 aa); and similar to others from Mycobacterium tuberculosis e.g. fadD6|MTCI364.18|Rv1206|O05307 PROBABLE FATTY-ACID-COA LIGASE (597 aa), FASTA score: (28.3% identity in 519 aa overlap); etc. Contains PS00455 Putative AMP-binding domain signature. BELONGS TO THE ATP-DEPENDENT AMP-BINDING ENZYME FAMILY. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1963367 | 1964965 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1779c|fadD1
MTDTIQSLLRQHVSDPTIAVKYGGLQWTWSQYLAESAARAAALITIADPQRPTHIGSLLGNTPEMLAQLAAAGLGGYVLCGLNTTRRGDALAADVRRADCQIVVTDADHRALLDGLDLAGARILDTSTPRWAELVAGDGAFVPYREVDTMDPFMMIFTSGTSGNPKAVPVSHLMATFAGRSLTERFGLTEQDTCYVSMPLFHSNAVVAGWAPAVVSGAAIAPATFSATGFLDDVRRYHATYMNYVGKPLAYILATPERDDDADNPLRVAFGNEANDKDIEEFSRRFGVQVEDGFGSTENAVIVIREPGTPPGSIGRGAHGVAVYNGETVTECAVARFDAHGALTNADEAIGELVNTTGSGFFTGYYNDPEANAERMRHGMYWSGDLAYRDSEGWIYLAGRTADWMRVDGENLTAAPIERILLRYKAINRVAVYAVPDEYVGDQVMAALVLRAGDTFDPDAFEAFLDAQPDLSTKARPRYIRIAADLPSTATHKVLKRQLIDEGTAVGKADTLWVREPRGSAYHHASGPAKAI
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