Gene Mb1838 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePPE33a
Gene length564 bp
IdentifierMb1838
Location 2041737 bp
Protein summary information
Molecular mass18762.1 Da
Isoelectric point3.7468
Protein length187 amino acids
Orthologs
M. tuberculosis H37RvRv1809
Cross-references
UniProtA0A1R3XZD0
InterProIPR000030
UniProtKB/TrEMBLQ7TZH6
General annotation
TypeCDS
FunctionUnknown
ProductPPE FAMILY PROTEIN [FIRST PART]
CommentsMb1838, PPE33a, len: 187 aa. Equivalent to 5' end of Rv1809, len: 468 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 187 aa overlap). Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins, most similar to RV1802AL022021|MTV049.23 (463 aa), FASTA scores: opt: 1238, E(): 0, (51.2% identity in 471 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, PPE33 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base transition (c-t) splits PPE33 into 2 parts, PPE33a and PPE33b, with PPE33a being truncated.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20417372042300+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1838|PPE33a
MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGPSSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISLVATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLAGQAAATG
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