Gene Mb1857 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegcvH
Gene length405 bp
IdentifierMb1857
Location 2062416 bp
Protein summary information
Molecular mass14179.6 Da
Isoelectric point3.7611
Protein length134 amino acids
Orthologs
M. tuberculosis H37RvRv1826
M. tuberculosis MTBC0mtbc0_001940
Cross-references
UniProtQ7TZG8
UniProtKB/TrEMBLX2BJ41, Q7TZG8
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLYCINE CLEAVAGE SYSTEM H PROTEIN GCVH
CommentsMb1857, gcvH, len: 134 aa. Equivalent to Rv1826,len: 134 aa, from Mycobacterium tuberculosis strain H37Rv,(99.3% identity in 134 aa overlap). Probable gcvH, glycine cleavage system H protein, highly similar to GCSH_ECOLI|P23884 glycine cleavage system H protein from Escherichia coli (129 aa), FASTA scores: opt: 428, E(): 2.2e-22, (47.8% identity in 134 aa overlap). Equivalent to MLCB1788.37c gcvH from Mycobacterium leprae (78.4% identity in 134 aa overlap). Contains PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. BELONGS TO THE GCVH FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20624162062820+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1857|gcvH
MSDIPSDLHYTAEHEWIRRSGDDTVRVGITDYAQSALGDVVFVQLPVIGTAVTAGETFGEVESTKSVSDLYAPISGKVSAVNSDLDGTPQLVNSDPYGAGWLLDIQVDSSDVAALESALTTLLDAEAYRGTLTE
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