Gene Mb1999
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE3A |
| Comments | Mb1999, yrbE3A, len: 134 aa. Similar to 5' end of Rv1964, len: 265 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 102 aa overlap). yrbE3A,hypothetical unknown integral membrane protein, part of mce3 operon and member of YrbE family (see citations below for more information), highly similar to Mycobacterium tuberculosis proteins O07412|Rv0167|MTCI28.07|yrbE1A (265 aa), O07791|Rv0587|MTCY19H5.35|yrbE2A (265 aa),Rv3501c|MTV023.08c|yrbE4A (254 aa), etc. Also highly similar to conserved hypothetical integral membrane proteins of yrbEA type, e.g. AAD24544.1|AF116213|YrbE1A from Mycobacterium leprae (112 aa); P45392|YRBE_ECOLI from Escherichia coli (260 aa), FASTA scores: opt: 893, E(): 0,(51.4% identity in 253 aa overlap); etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a large deletion of 12719 bp (RD7) leads to the loss of the COOH part of yrbE3A, the entire mce3 operon and the following genes up to Mb2000 compared to Mycobacterium tuberculosis strain H37Rv. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2199335 | 2199739 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb1999|yrbE3A
MVIVADKAAGRVADPVLRPVGALGDFFAMTLDTSVCMFKPPFAWREYLLQCWFVARVSTLPGVLMTIPWAVISGFLFNVLLTDIGAADFSGTGCAIFTVNQSRGTGSLERGRFIGPQDHRVAAALEVTAPLLRS
Bibliography
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