Gene Mb2005 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS35
Gene length1677 bp
IdentifierMb2005
Location 2205160 bp
Protein summary information
Molecular mass53767.8 Da
Isoelectric point3.967
Protein length558 amino acids
Orthologs
M. tuberculosis H37RvRv1983
M. tuberculosis MTBC0mtbc0_002106
Cross-references
UniProtA0A1R3XZU6
InterProIPR000084
UniProtKB/TrEMBLQ7TZ65
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs35
CommentsMb2005, PE_PGRS35, len: 558 aa. Equivalent to Rv1983, len: 558 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 558 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins. Similar to other PE proteins e.g. Rv0977, etc. Contains PS00141 Eukaryotic and viral aspartyl proteases active site.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22051602206836+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2005|PE_PGRS35
MSFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQTLNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRPLIGDGAPGTATSPNGGAGGLLYGNGGNGYSATASGVGGGAGGSAGLIGNGGAGGAGGPNAPGGAGGNGGWLLGNGGIGGPGGASSIPGMSGGAGGTGGATGLLGWGANGGAGGLGDGVGVDRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEPTVHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYSGGLYYIFATYTTTVDFGNGIVTAPTAVNVVLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGVLGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGSGTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPVYIDYSPSGIGTTVFDHPA
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