Gene Mb2010 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameerm(37)
Gene length540 bp
IdentifierMb2010
Location 2210596 bp
Protein summary information
Molecular mass19606.0 Da
Isoelectric point12.4065
Protein length179 amino acids
Orthologues
M. tuberculosisRv1988
Cross-references
UniProtA0A1R3XZX2
InterProIPR001737, IPR020598
UniProtKB/TrEMBLQ7TZ64
General annotation
TypeCDS
FunctionUnknown
Productprobable 23s rrna methyltransferase erm(37)
CommentsMb2010, -, len: 179 aa. Equivalent to Rv1988, len: 179 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 179 aa overlap). Probable methyltransferase (EC 2.1.1.-), similar to ERME_SACER|P07287 rrna adenine n-6-methyltransferase (370 aa), FASTA scores: opt: 259, E(): 2e-11, (35.1% identity in 171 aa overlap); contains PS00092 N-6 Adenine-specific DNA methylases signature. Also similar to Mycobacterium tuberculosis Rv1010 ksgA 16S rRNA dimethyltransferase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22105962211135+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2010|erm(37)
MSALGRSRRAWGWHRLHDEWAARVVSAAAVRPGELVFDIGAGEGALTAHLVRAGARVVAVELHPRRVGVLRERFPGITVVHADAASIRLPGRPFRVVANPPYGISSRLLRTLLAPNSGLVAADLVLQRALVCKFASRNARRFTLTVGLMLPRRAFLPPPHVDSAVLVVRRRKCGDWQGR
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