Gene Mb2014A in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemazE6
Gene length249 bp
IdentifierMb2014A
Location 2213559 bp
Protein summary information
Molecular mass9290.34 Da
Isoelectric point4.3758
Protein length82 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_002118
M. tuberculosis H37RvRv1991A
Cross-references
UniProtP0CL58
UniProtKB/TrEMBLX2BJQ6, P0CL58
General annotation
TypeCDS
FunctionUnknown
ProductAntitoxin MazE6
CommentsMb2014A, len: 82 aa. Equivalent to Rv1991A len: 82 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 82 aa overlap). Transferred from H37Rv annotation using Rapid Annotation Transfer Tool (Nucleic Acids Res. 2011 May; 39(9): e57). MazE6, antitoxin, part of toxin-antitoxin (TA) operon with Rv1991c. Similar to ChpI of L. interrogans, FASTA scores: opt: 134, E(): 0.024,29.762% identity (65.476% similar) in 84 aa overlap. Note that Pandey and Gerdes, 2005 predicts a different N-terminus, adding 10 amino acids.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22135592213807-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2014A|mazE6
MKTAISLPDETFDRVSRRASELGMSRSEFFTKAAQRYLHELDAQLLTGQIDRALESIHGTDEAEALAVANAYRVLETMDDEW
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