Gene Mb2017c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecmtr
Gene length357 bp
IdentifierMb2017c
Location 2216544 bp
Protein summary information
Molecular mass12495.4 Da
Isoelectric point6.7412
Protein length118 amino acids
Orthologues
M. tuberculosisRv1994c
Cross-references
UniProtP67732
UniProtKB/TrEMBLX2BJI3, P67732
General annotation
TypeCDS
FunctionUnknown
Productmetal sensor transcriptional regulator cmtr (arsr-smtb family)
CommentsMb2017c, -, len: 118 aa. Equivalent to Rv1994c,len: 118 aa, from Mycobacterium tuberculosis strain H37Rv,(100.000% identity in 118 aa overlap). Probable transcription regulator, similar to MERR_STRLI|P30346 probable mercury resistance operon repressor (125 aa),FASTA scores: opt: 199, E(): 3e-08, (36.3% identity in 102 aa overlap). Contains probable helix-turn-helix motif at aa 36-57 (+3.78 SD).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22165442216900-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2017c|cmtr
MLTCEMRESALARLGRALADPTRCRILVALLDGVCYPGQLAAHLGLTRSNVSNHLSCLRGCGLVVATYEGRQVRYALADSHLARALGELVQVVLAVDTDQPCVAERAASGEAVEMTGS
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