Gene Mb2049c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | CONSERVED HYPOTHETICAL PROTEIN |
| Comments | Mb2049c, RvD1-Rv2024c, len: 1606 aa. Equivalent to Rv2024c and similar to Rv2020c, len: 515 aa and 99 aa,from Mycobacterium tuberculosis strain H37Rv, (99.2% identity in 506 aa overlap and 67.0% identity in 97 aa overlap). Rv2024c: Conserved hypothetical protein. Identical to N-terminal part of much larger hypothetical protein, RvD1-Rv2024c' (1606 aa), from Mycobacterium bovis BCG: CAB44655.1|Y18605|13881753|AAK46361.1|AE007059 so probably truncated. Part of RvD1 chromosomal deletion region. Also similar to hypothetical protein from Helicobacter pylori. FASTA scores: AE0005|HPAE000580_2 Helicobacter pylori (607 aa) opt: 64, E(): 0, (36.2% identity in 464 aa overlap). Rv2020c: Conserved hypothetical protein, nearly identical to C-terminal part of hypothetical protein RvD1-Rv2024c' from Mycobacterium bovis BCG (1606 aa) emb|CAB44655.1| (Y18605). Corresponds to deletion region RvD1 so probably truncated protein. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, a large deletion region (RvD1) exists in between Rv2023 and Rv2024. In Mycobacterium bovis a 5000 bp insertion at this region results in Mb2049c being a much larger product with a different COOH part (1606 aa versus 515 aa). |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2249336 | 2254156 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2049c|Mb2049c
MGSVHDVIEAFRKAPSNAERGTKFEQLMVRYFELDPTMAQQYDAVWRWIDWPERRGRTDTGIDLVARERDTGNYTAIQCKFYEPTHTLAKGDIDSFFTASGKTGFTNRVIISTTDRWGRNAEDALADQLVPVQRIGMAEIAESPIDWDIAWPAGDLQVNLTPAKRHELRPHQQQAIDAVFRGFAVGNDRGKLIMACGTGKTFTALKIAERIAADNGGSARILLLVPSISLLSQTLREWTAQSELDVRAFAVCSDTKVSRSAEDYHVHDVPIPVTTDARVLLHEMAHRRCAQGLTVVFCTYQSLPTVAKAQRLGVDEFDLVMCDEAHRTTGVTLAGDDESNVVRVHDGQYLKAARRLYMTATPRIFTESIKDRADQHSAELVSMDDELTFGPEFHRLSFGEAVERGLLTDYKVMVLTVDQGVIAPRLQQELSGVSGELMLDDASKIVGCWNGLAKRSGTGIVAGEPPMRRAVAFAKDIKTSKQVAELFPKVVEAYRELVDDGPGLACSVRHVDGTFNALVRNEQLAWLKGVVAEDECRILSNARCLSEGVDVPALDAVLFLNPRNSIVDVVQSVGRVMRKSPGKDYGYVILPVAVPEGVEPSAALADNKRFKVVWQVLNALRSHDERFDAMVNSIALNVKPTKTGEGSDKLLGGHIGPTSDEAGPAVAEQLAMFSLSQWQEAIYARIVDKVGTRTYWEQWAADVADIAATLTTRIHALLGGADATAAAAFEQFLAGLRDNLNDSITPDDAISMLSQHLITKPVFDALFAGHDFASHNPVSRAMQKMVDTVGGAGLEAETARLEGFYESVRRRAGEVTSAEGKQQVIAELYEKFFRIGFKKQAEALGIVYTPVEVVDFIVRAADFVSRKHFGRGLTDEGVHILDGFAGTGTFITRLLQSDLITAADLTRKYSQELHANEIMLLAYYIAAVNIESTYHALAGKTADADAYEPFPGMALADTFQISEAGDSMDAIMFPYNNARILRQLATPISVIIGNPPYSVGQSSANDLNANVKYPTLDGRIEQTYAKRSTAQLKNSLYDSYIRAFRWATDRIGDNGVVGFVSNGGYIDGNTADGMRLSLADDYAAVYVYNLRGNQRTAGELSRQEGGKVFGGGSRNTVAIFLGIKDPKHSGPCDVLYRDIGDYLSREEKLRIVGDGYLDTVEWQTVTPNLHGDWVNQRDDAFSAWPVIGDKKAALDVTRVFANYSAGLKTSRDAWCYNFSRGALEANIGRTIDFYNSEVDRINEIRGRDAKTPPVDALITVDSAKFSWDRINKRQVAQGIRIEFAPAGMRLGTYRPFTKEHAYLDPNQQLNNCTYQLPSMFPTPEHGNVGYYVVGMGSDKPFSCLMLNAIPDLAFWGSSNGQFFPRWTYEKTEPRDGELDFESTTNAEVDDHGYRRVDNITGVILKLYRDTIGDQVTKDDIFYYVYGLLHDPAYRTKYAADLKKMLPHIPTPETRERFDQLASAGRKLADLHVGYESVKPYPLDVQLKPGADPEDRETWRVEKMKWKSKQDHSTIIYNSRVTIAGIPDEAERYLLGSRSALGWIIDRYRVTTDKASGIVNDPNDWCDEHANPTYIVDLIKKVTTVSVETMKIVDSIVALASAGSDST
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