Gene Mb2088c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecobN
Gene length3585 bp
IdentifierMb2088c
Location 2301082 bp
Protein summary information
Molecular mass129182.0 Da
Isoelectric point4.8649
Protein length1194 amino acids
Orthologs
M. tuberculosis H37RvRv2062c
M. tuberculosis MTBC0mtbc0_002195
Cross-references
UniProtA0A1R3Y298
InterProIPR003672, IPR011953
UniProtKB/TrEMBLQ7VER8
General annotation
TypeCDS
FunctionUnknown
Productcobalamin biosynthesis protein cobn
CommentsMb2088c, cobN, len: 1194 aa. Equivalent to Rv2062c,len: 1194 aa, from Mycobacterium tuberculosis strain H37Rv, (99.9% identity in 1194 aa overlap). Probable cobN,cobalamin biosynthesis protein - very similar to COBN_PSEDE P29929 cobn protein. Pseudomonas denitrifica (1275 aa), FASTA scores, opt: 831, E(): 0, (37.5% identity in 983 aa overlap). Also similar to several Mg2+-chelatases e.g. H64479 magnesium chelatase subunit homolog (1226 aa )opt: 962 E(): 0; (27.3% identity in 846 aa overlap)
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23010822304666-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2088c|cobN
MPEPTVLLLSTSDTDLISARSSGKNYRWANPSRLSDLELTDLLAEASIVVIRILGGYRAWQSGIDTVIAGGVPAALVSGEQAADAELTDRSTVAAGTALQAHIYLAHGGVDNLRELHAFLCDTVLMTGFGFTPPVATPTWGVLERPDAGKTGPTIAVLYYRAQHLAGNTGYVEALCRAIEDAGGRPLPLYCASLRTAEPRLLERLGGADAMVVTVLAAGGVKPAAASAGGDDDSWNVEHLAALDIPILQGLCLTSPRDQWCANDDGLSPLDVASQVAVPEFDGRIITVPFSFKEIDDDGLISYVADPERCARVAGLAVRHARLRQVAPADKRVALVFSAYPTKHARIGNAVGLDTPASAVALLQAMRQRGYRVGDLPGVESNDGDALIHALIECGGHDPDWLTEGQLAGNPIRVSAKEYRDWFATLPAELTDVVTAYWGPPPGELFVDRSHDPDGEIVIAALRAGNLVLMVQPPRGFGENPVAIYHDPDLPPSHHYLAAYRWLDTGFSNGFGAHAVVHLGKHGNLEWLPGKTLGMSASCGPDAALGDLPLIYPFLVNDPGEGTQAKRRAHAVLVDHLIPPMARAETYGDIARLEQLLDEHASVAALDPGKLPAIRQQIWTLIRAAKMDHDLGLTERPEEDSFDDMLLHVDGWLCEIKDVQIRDGLHILGQNPTGEQELDLVLAILRARQLFGGAHAIPGLRQALGLAEDGTDERATVDQTEAKARELVAALQATGWDPSAADRLTGNADAAAVLRFAATEVIPRLAGTATEIEQVLRALDGRFIPAGPSGSPLRGLVNVLPTGRNFYSVDPKAVPSRLAWEAGVALADSLLARYRDEHGRWPRSVGLSVWGTSAMRTAGDDIAEVLALLGVRPVWDDASRRVIDLAPMQPAELGRPRIDVTVRISGFFRDAFPHVVTMLDDAVRLVADLDEAAEDNYVRAHAQADLAHHGDQRRATTRIFGSKPGTYGAGLLQLIDSRSWRDDADLAQVYTAWGGFAYGRDLDGREAIDDMNRQYRRIAVAAKNTDTREHDIADSDDYFQYHGGMVATVRALTGQAPAAYIGDNTRPDAIRTRTLSEETTRVFRARVVNPRWMAAMRRHGYKGAFEMAATVDYLFGYDATAGVMADWMYEQLTQRYVLDAQNRTFMTESNPWALHGMAERLLEAAGRGLWAQPAPETLDGLRQVLLETEGDLEA
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