Gene Mb2209 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadd15
Gene length513 bp
IdentifierMb2209
Location 2427194 bp
Protein summary information
Molecular mass19306.1 Da
Isoelectric point10.4122
Protein length170 amino acids
Orthologs
M. tuberculosis H37RvRv2187
Cross-references
UniProtUPI00001A90B9
InterProIPR000873
UniProtKB/TrEMBLQ7TYX9
General annotation
TypeCDS
FunctionUnknown
ProductHYPOTHETICAL PROTEIN
CommentsMb2209, -, len: 170 aa. Equivalent to 5' end of Rv2187, len: 600 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 90 aa overlap). Probable fadD15, long-chain-fatty-acid-CoA ligase (EC 6.2.1.3),similar to several e.g. P44446|LCFH_HAEIN PUTATIVE LONG-CHAIN-FATTY-ACID--CoA LIGASE from Haemophilus influenzae (607 aa), FASTA scores: (607 aa) opt: 992, E(): 0, (31.5% identity in 578 aa overlap); etc. Contains PS00455 Putative AMP-binding domain signature. BELONGS TO THE ATP-DEPENDENT AMP-BINDING ENZYME FAMILY. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, fadD15 exists as a single gene. In Mycobacterium bovis, a frameshift due to single base deletion (t-*) splits fadD15 into 2 parts, Mb2209 and fadD15.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24271942427706+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2209|fadd15
MREISVPAPFTVGEHDNVAAMVFEHERDDPDYVIYQRLIDGVWTDVTCAEAANQIRAAALGLISLGVQAGDRVVIFSATRYEWAILDFAIRLWVRSPYRSTRPRQRSRCAGFYKTPKRWCCSPKPTHTRQWSPNSPAACPPCGRYCRSPVRVPTRSIGSRRRAPRSTRPS
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