Gene Mb2235 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2235
Gene length1137 bp
IdentifierMb2235
Location 2456337 bp
Protein summary information
Molecular mass39775.1 Da
Isoelectric point4.4085
Protein length378 amino acids
Orthologues
M. tuberculosisRv2212
Cross-references
UniProtP64266
UniProtKB/TrEMBLX2BK46, P64266
General annotation
TypeCDS
FunctionUnknown
Productadenylyl cyclase (atp pyrophosphate-lyase) (adenylate cyclase)
CommentsMb2235, -, len: 378 aa. Equivalent to Rv2212, len: 378 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 378 aa overlap). Conserved hypothetical protein. Some similarity to adenylate cyclases, e.g. SW:CYAA_STRCO P40135 (29.2% identity in 291 aa overlap); ttg at 24614 in MTCY190 has a better rbs. Contains possible helix-turn-helix motif at aa 64-85,(+2.72 SD). Also similar to Rv1264 and Rv1647
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24563372457473+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2235|Mb2235
MYDSLDFDALEAAGIANPRERAGLLTYLDELGFTVEEMVQAERRGRLFGLAGDVLLWSGPPIYTLATAADELGLSADDVARAWSLLGLTVAGPDVPTLSQADVDALATWVALKALVGEDGAFGLLRVLGTAMARLAEAESTMIRAGSPNIQMTHTHDELATARAYRAAAEFVPRIGALIDTVHRHHLASARTYFEGVIGDTSASVTCGIGFADLSSFTALTQALTPAQLQDLLTEFDAAVTDVVHADGGRLVKFIGDAVMWVSSSPERLVRAAVDLVDHPGARAAELQVRAGLAYGTVLALNGDYFGNPVNLAARLVAAAAPGQILAAAQLRDMLPDWPALAHGPLTLKGFDAPVMAFELHDNPRARDADTPSPAASD
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