Gene Mb2260c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecobD
Gene length942 bp
IdentifierMb2260c
Location 2487582 bp
Protein summary information
Molecular mass33004.2 Da
Isoelectric point11.31
Protein length313 amino acids
Orthologs
M. tuberculosis H37RvRv2236c
M. tuberculosis MTBC0mtbc0_002376
Cross-references
UniProtQ7VEN1
UniProtKB/TrEMBLX2BKH6, Q7VEN1
General annotation
TypeCDS
FunctionUnknown
Productprobable cobalamin biosynthesis transmembrane protein cobd
CommentsMb2260c, cobD, len: 313 aa. Equivalent to Rv2236c,len: 313 aa, from Mycobacterium tuberculosis strain H37Rv,(99.4% identity in 313 aa overlap). Probable cobD,conserved membrane protein, similar to PIR:S52223 Rhodobacter capsulatus 945 protein BluD (39.0% identity in 287 aa overlap) involved in cobinamide synthesis, and to SW:COBD_PSEDE Pseudomonas dentrificans cobD protein (37.5% identity in 269 aa overlap), also SW:CBIB_SALTY Salmonella typhimurum cbiB protein (35.5% identity in 304 aa overlap)
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24875822488523-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2260c|cobD
MFASIWQTRAVGVLIGCLLDVVFGDPKRGHPVALFGRAAAKLEQITYRDGRVAGAVHVGLLVGAVGLLGAALQRLPGRCWPVAATATATWAALGGTSLARTGRQISDLLERDDVEAARRLLPSLCGRDPAQLGGPGLTRAALESVAENTADAQVVPLLWAASSGVPAVLGYRAINTLDSMIGYRSPRYLRFGWAAARLDDWANYVGARATAVLVVICAPVVGGSPRGAVRAWRRDAARHPSPNAGVVEAAFAGALDVRLGGPTRYHHELQIRPTLGDGRSPKVADLRRAVVLSRVVQAGAAVLAVMLVYRRRP
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