Gene Mb2285c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | CONSERVED HYPOTHETICAL PROTEIN |
| Comments | Mb2285c, -, len: 502 aa. Equivalent to Rv2262c and Rv2261c, len: 360 aa and 140 aa, from Mycobacterium tuberculosis strain H37Rv, (94.7% identity in 357 aa overlap and 100.0% identity in 140 aa overlap). Conserved hypothetical protein, with function unknown but some similarity to N-terminal 70% of P23930|P77703|LNT_ECOLI|CUTE|B0657 APOLIPOPROTEIN N-ACYLTRANSFERASE (EC 2.3.1.-) from Escherichia coli strain K12 (512 aa), FASTA scores: opt: 239, E(): 1.6e-07,(30.4% identity in 359 aa overlap). Note that neighboring ORF shows similarity to N -terminal part of PCC6803 apolipoprotein N-acyltransferase from Synechocystis sp.,suggesting possibility of frameshift. Sequence of clones from two sources has been checked but no error found. Appear to be two extra bases at position 1876970 compared to CDC1551 strain. Conserved hypothetical protein, with function unknown but some similarity to C-terminal end of PCC6803 apolipoprotein N-acyltransferase from Synechocystis sp. Note that next ORF shows similarity to N-terminal part of P74055 APOLIPOPROTEIN N-ACYLTRANSFERASE from Escherichia coli (519 aa), FASTA scores: opt: 142,E(): 0.007, (29.9% identity in 117 aa overlap), suggesting possible frameshift. Sequence of clones from two sources has been checked but no error found. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv2262c and Rv2261c exist as 2 genes. In Mycobacterium bovis, a 2 bp deletion (ct-*) results in a single product which is more similar to Rv2262c. |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2512998 | 2514506 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2285c|Mb2285c
MALRAGARRQPVIGCAAALVFGGLPALAFPAPSWWWLAWFGLVPLLLVVRAAPTSWEGALRAWTGMGGFVLATQYWLVTSAGPMLVLLAAGLGVLWLPAGWLAHRLLSVPVTTCRVGAALVVVPSAWVAAEAVRSWQSLGGPWALLGASQWSQPVTLASASLGGVWLTSFLLVATNTAIASVLVCRATGGRLVALGCVIGCAGLGPASYLLGSVPVGGPTVRVALVQAGDIADAAARLAAGEEFTAAVADQRPDLVVWGESSVGQDLTRHPDVLARLAELSQRVGADLLVNVDAPAPDGGIYKSAVLVGAHEAVGSYRKTRLVPFGEYVPLRPLFGWITRYSKAAAKDRQRGAGPVVLAVNSLHIAPLISYEMTFSDLTRHAARLGAALLVYQSSTSTFQGSWAQPQLAAQPAVRAVEAGIPAVHASLSGDSSAFDTRGRRLAWCSAEFNGAIVVNVPLASNVTLYLRLGDWVPVTAFVVMGAGFAVFLRRSLARVSDCADK
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