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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPA
CommentsMb2343, uspA, len: 290 aa. Equivalent to Rv2316,len: 290 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 290 aa overlap). Probable uspA,sugar-transport integral membrane protein ABC transporter (see citation below), most similar to Q9CBN8|USPA|ML1768 SUGAR TRANSPORT INTEGRAL MEMBRANE PROTEIN from Mycobacterium leprae (328 aa), FASTA scores: opt: 1593,E(): 1.9e-93, (82.35% identity in 289 aa overlap); and similar to O32940|ML1426|MLCB2052.28 POSSIBLE SUGAR TRANSPORT PROTEIN (PROBABLE ABC-TRANSPORT PROTEIN, INNER MEMBRANE COMPONENT) from Mycobacterium leprae (319 aa),FASTA scores: opt: 600, E(): 9.2e-31, (34.25% identity in 295 aa overlap). Also similar to other proteins involved in transport e.g. Q9X860|SCE134.05c PUTATIVE BINDING PROTEIN DEPENDENT TRANSPORT PROTEIN from Streptomyces coelicolor (327 aa), FASTA scores: opt: 639, E(): 3.2e-33,(40.45% identity in 272 aa overlap); Q9K6N9|BH3689 SUGAR TRANSPORT SYSTEM (PERMEASE) from Bacillus halodurans (300 aa), FASTA scores: opt: 590, E(): 3.7e-30, (35.65% identity in 289 aa overlap); etc.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25664332567305+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2343|uspA
MRDAPRRRTALAYALLAPSLVGVVAFLLLPILVVVWLSLHRWDLLGPLRYVGLTNWRSVLTDSGFADSLVVTAVFVAIVVPAQTVLGLLAASLLARRLPGTGLFRTLYVLPWICAPLAIAVMWRWILAPTDGAISTVLGHRIEWLTDPGLALPVVSAVVVWTNVGYVSLFFLAGLMAIPQDIHNAARTDGASAWQRFWRITLPMLRPTMFFVLVTGIISAAQVFDTVYALTGGGPQGSTDLVAHRIYAEAFGAAAIGRASVMAVVLFVILVGATVVQHLYFRRRISYELT
      
Bibliography
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