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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT)
CommentsMb2363, -, len: 229 aa. Equivalent to Rv2335, len: 229 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 229 aa overlap). Probable cysE, serine acetyltransferase (EC 2.3.1.30), equivalent to O32979|CYSE|ML0838 SERINE ACETYLTRANSFERASE from Mycobacterium leprae (227 aa), FASTA scores: opt: 1152,E(): 9.6e-62, (76.4% identity in 229 aa overlap). Also highly similar, except in C-terminal part, to others e.g. Q9HXI6|CYSE|PA3816 O-ACETYLSERINE SYNTHASE from Pseudomonas aeruginosa (258 aa), FASTA scores: opt: 737,E(): 6e-37, (61.3% identity in 168 aa overlap); P23145|NIFP_AZOCH PROBABLE SERINE ACETYLTRANSFERASE from Azotobacter chroococcum mcd 1 (269 aa), FASTA scores: opt: 718, E(): 8.4e-36, (55.45% identity in 220 aa overlap); Q06750|CYSE_BACSU SERINE ACETYLTRANSFERASE from Bacillus subtilis (217 aa), FASTA scores: opt: 640, E(): 3.1e-31,(48.0% identity in 200 aa overlap); etc. Contains PS00101 Bacterial hexapeptide-repeat containing-transferases signature. BELONGS TO THE CYSE/LACA/LPXA/NODL FAMILY OF ACETYLTRANSFERASES. COMPOSED OF MULTIPLE REPEATS OF [LIV]-G-X(4).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25873282588017+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2363|cysE
MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFTRILTGVDIHPGAVIGARVFIDHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVVVGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIWHGEDFSI
      
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