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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productprobable zinc uptake regulation protein zur
CommentsMb2380, furB, len: 130 aa. Equivalent to Rv2359,len: 130 aa, from Mycobacterium tuberculosis strain H37Rv,(99.2% identity in 130 aa overlap). Probable furB, ferric uptake regulation protein, equivalent to FURB|ML0824|Q9CCG6 PUTATIVE FERRIC UPTAKE REGULATORY PROTEIN from Mycobacterium leprae (131 aa), FASTA scores: opt: 765, E(): 1.7e-43, (86.9% identity in 130 aa overlap). Also highly similar to FERRIC UPTAKE REGULATION PROTEINS e.g. Q9L2H5|SCC121.11 PUTATIVE METAL UPTAKE REGULATION PROTEIN from Streptomyces coelicolor (139 aa),FASTA scores: opt: 547, E(): 3.4e-29, (59.4% identity in 133 aa overlap); P06975|FUR_ECOLI from Escherichia coli (148 aa), FASTA scores: opt: 322, E(): 1.9e-14, (37.9% identity in 132 aa overlap); P45599|FUR_KLEPN FERRIC UPTAKE REGULATION PROTEIN from Klebsiella pneumoniae (155 aa), FASTA scores: opt: 314, E(): 6.7e-14, (36.35% identity in 132 aa overlap); etc. BELONGS TO THE FUR FAMILY.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26097212610113+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2380|zur
MSAAGVRSTRQRAAISTLLETLDDFRSAQELHDELRRRGENIGLTTVYRTLQSMASSGLVDTLRTDTGESVYRRCSEHHHHHLVCRSCGSTIEVGDHEVEAWAAEVATKHGFSDVSHTIEIFGTCSDCRS
      
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