Gene Mb2407c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | isochorismate synthase mbti |
| Comments | Mb2407c, mbtI, len: 450 aa. Equivalent to Rv2386c,len: 450 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 450 aa overlap). Putative mbtI,isochorismate synthase (see citations below), similar to Q9X9I8|IRP9 SALICYLATE SYNTHETASE from Yersinia enterocolitica (434 aa), FASTA scores: opt: 887, E(): 7.5e-48, (37.45% identity in 422 aa overlap); and similar in C-terminal region to many anthranilate synthases component I (EC 4.1.3.27) e.g. Q9Z4W7|TRPE_STRCO|SCE8.07c from Streptomyces coelicolor (511 aa), FASTA scores: opt: 509, E(): 3e-24, (40.4% identity in 255 aa overlap); P33975|TRPE_HALVO from Halobacterium volcanii (Haloferax volcanii) (523 aa) FASTA scores: opt: 488, E(): 6.2e-23,(34.2% identity in 298 aa overlap); and similar to Q08653|TRPE_THEMA|TM0142 ANTHRANILATE SYNTHASE COMPONENT I from Thermotoga maritima (461 aa), FASTA scores: opt: 478,E(): 2.3e-22, (28.4% identity in 440 aa overlap); etc. COULD BE BELONG TO THE ANTHRANILATE SYNTHASE COMPONENT I FAMILY. Note that previously known as trpE2, an anthranilate synthase component I (EC 4.1.3.27). |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2646724 | 2648076 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2407c|mbtI
MSELSVATGAVSTASSSIPMPAGVNPADLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAIDRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVARQ
Bibliography
No article yet recorded
