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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [FIRST PART]
CommentsMb2416, -, len: 146 aa. Equivalent to 5' end of Rv2395, len: 667 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 44 aa overlap). Probable conserved integral membrane protein, similar to AAK24613|CC2646 OLIGOPEPTIDE TRANSPORTER/OPT FAMILY PROTEIN from Caulobacter crescentus (666 aa), FASTA scores: opt: 1638, E(): 4.8e-86, (51.0% identity in 658 aa overlap); Q9PIS5|CJ0204 PUTATIVE INTEGRAL MEMBRANE PROTEIN from Campylobacter jejuni (665 aa), FASTA scores: opt: 1484, E(): 2.9e-77, (40.6% identity in 658 aa overlap); and P44016|Y561_HAEIN hypothetical integral membrane protein from Haemophilus influenzae (635 aa), FASTA scores: opt: 1449, E(): 2.8e-75, (42.15% identity in 624 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv2395 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base insertion (*-t) splits Rv2395 into 2 parts,Mb2416 and Mb2417.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26581432658583+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2416|Mb2416
MSGATVGAREITIRGVVLGALITLVFTAANVYLGLRVGLTFATSHTGRGDLDGRAAVVRQPLSGGEQYCSDDRVGGRHAVVDHLRVTGTAHDRLVERVSVLDNGGGVCTGRDPWRHVLNSVAPRTRHRIRPAVPRRRCRSRGSQDR
      
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