Gene Mb2426c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelppR
Gene length756 bp
IdentifierMb2426c
Location 2668604 bp
Protein summary information
Molecular mass26352.9 Da
Isoelectric point6.507
Protein length251 amino acids
Cross-references
InterProIPR026954
UniProtKB/TrEMBLQ7TYN4
SWISS-MODELA0A1R3Y147
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED LIPOPROTEIN LPPR
CommentsMb2426c, lppR, len: 251 aa. Equivalent to Rv2403c,len: 251 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 251 aa overlap). Probable lppR,conserved lipoprotein, with weak similarity with MYCOBACTERIAL SERINE/THREONINE PROTEIN KINASES (EC 2.7.1.-) e.g. AAK45563|MT1304 from Mycobacterium tuberculosis strain CDC1551 (626 aa), FASTA scores: opt: 186, E(): 0.00023, (24.4% identity in 238 aa overlap), and the C-terminal part of Q11053|Rv1266c|MTCY50.16|PKNH_MYCTU from Mycobacterium tuberculosis (626 aa), FASTA scores: opt: 185, E()= 0.00027, (24.35% identity in 238 aa overlap). Has signal peptide and appropriate positioned prokaryotic lipoprotein attachment site (PS00013). Could belong to the SER/THR FAMILY of protein kinases.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26686042669359-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2426c|lppR
MTNRWRWVVPLFAVFLAAGCTTTTTGKAGLAPNAVPRPLMGSLIQRVPLDGAALSTLLNQPFQALPPFPPVFGGSDSLGDSDVSARPADCVGVGYLTQRNVYRSVEVKSVARVSWRHDGSSVKVDDLDEGVVALPSAAAADDLFARFSAQWKECDGTTLTVPASAFGQRSITDVRVADSVVAATVSLRRGTHSILASVPQARAVGVRGNCVVEVAVTFFGITHPSDQGSADISTSAVDIAHAMMDRISELS
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