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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN
CommentsMb2437c, -, len: 523 aa. Similar to Rv2414c, len: 514 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 483 aa overlap). Conserved hypothetical protein, showing some similarity with COME OPERON PROTEINS 3 (COMEC OR COME3) e.g. Q9RTB1|DR1854 PUTATIVE COMPETENCE PROTEIN COMEC/REC2 from Deinococcus radiodurans (755 aa), FASTA scores: opt: 311, E(): 8.2e-11, (27.3% identity in 538 aa overlap); P73100|COME|SLL1929 COME PROTEIN from Synechocystis sp. strain PCC 6803 (709 aa), FASTA scores: opt: 302, E(): 2.6e-10, (26.3% identity in 323 aa overlap) (no similarity on N-terminus); P39695|CME3_BACSU COME OPERON PROTEIN 3 from Bacillus subtilis (776 aa), FASTA scores: opt: 273,E(): 1.4e-08, (25.2% identity in 282 aa overlap) (no similarity on N-terminus); etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a single base insertion (*-t) leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis H37Rv (523 aa versus 514 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26794902681061-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2437c|Mb2437c
MGFGASRLDVRLVPAALVSWIVTAAGIVWPIGNVCALCCVVVALGGGALWWCVARRSWHAPRLGSISAGLVAVGMVGAGYGLAVALRSEAVDRHPITVAFGTSALVTVTPSESPVSLGRGRLMFRATVQRLRDDETSGRVVVFARALDFGELMVGQPVQFRARISRPARHDLTVAVFNATGRPTVGRAGPVHRAAHIVRHRFAAAVREVLPADQATMLPALVLGDTSTVTALTSREFRAAGLTHLTAVSGANVTIVCAAALVSARLIGPRAAVVCAAVALVAFVILVQPTASVLRAAVMGAIALVGMLSARRRQAIPALSGSVLVLLAAAPHLAVDIGFALSVAATGALVVIAPVWSRRLVDRGCPKVLADALAVAAAAQLVTAPLVAAISGRVSLVAVVANLAVAAVIAPITVLGSVAAVLVVPWPAGAQVLIRFTGPEVWWVLRVAHWASGVPAATVPVAAGLPGVLLVGGATVFTVAQWRLALVSRGHVQNDGGGRHMSACLVAVRAGRPFVTPSWGERG
      
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